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Are Epogen and Procrit interchangeable? On, the FDA announced the approval of Retacrit (epoetin alfa-epbx), Hospira/Pfizer's biosimilar to Amgen's Epogen (epoetin alfa) and Janssen's Procrit (epoetin alfa). Retacrit has been approved as a biosimilar to Epogen / Procrit, not as an interchangeable product.
What is the role of erythropoietin? The role of erythropoietin is to control red blood cell production by regulating the differentiation and proliferation of erythroid progenitor cells in the bone marrow. Produced primarily in the kidney, erythropoietin circulates in the plasma and acts on target cells in the bone marrow.
Why is Epogen given after dialysis? Anemia Due To Chronic Kidney Disease. Epogen is indicated for the treatment of anemia due to chronic kidney disease (CKD), including patients on dialysis and not on dialysis to decrease the need for red blood cell (RBC) transfusion.
Does EPO show up in urine? EPO, or erythropoietin, is a natural substance produced within the kidneys that stimulates the creation of new red blood cells. Blood-boosting drugs like EPO, if injected, are only detectable in the urine or blood for a short window of time.
What is Procrit and how does it work? PROCRIT works like EPO — it causes your bone marrow to make more red blood cells. This, in turn, raises your level of hemoglobin, a protein found in red blood cells that carries oxygen to all parts of the body. Increasing your hemoglobin level may lessen the need for a blood transfusion.
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