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Finally, the place of each drug in therapy is compared between current worldwide guidelines.
Take twice as long breathing out as you did breathing in, so that there is pressure in the windpipe and chest, and trapped air is forced out.
Montelukast reduces asthma exacerbations in 2- to 5-year-old children with intermittent asthma.
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After a 2-week run-in period, eligible patients were randomly assigned, in permuted blocks with stratification according to country and smoking status, to treatment with the combination of salmeterol at a dose of 50 μg and fluticasone propionate at a dose of 500 μg (Advair Diskus, Seretide, GlaxoSmithKline) or salmeterol (Serevent, GlaxoSmithKline) alone at a dose of 50 μg, fluticasone propionate (Flovent Diskus, Flixotide, GlaxoSmithKline) alone at a dose of 500 μg, or placebo, all taken in the morning and the evening for 3 years.
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This nongenomic action occurs within seconds to a few minutes, and this could explain why the protective action of fluticasone on the vascular effect of salmeterol is immediate.
Once-daily QVA149 provides clinically meaningful improvements in lung function and clinical outcomes.
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Exposure to particulate matter, irritants, organic dusts, and sensitizing agents can cause an increase in airway hyperresponsiveness (), especially in airways already damaged by other occupational exposures, cigarette smoke, or asthma.
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ICS and LABA can be administered via two separate inhalers but using a combination inhaler appears more convenient and may improve compliance.
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As is reflected in the routinely advocated doses for human use, formoterol has a higher potency than salmeterol ().
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It is a prepressurized inhaler with medication and a propellant, which when actuated will give one dose of the drug for a single inspiration.
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It is considered an integral part of asthma management for patients and doctors.
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None of the existing medications for COPD has been shown to modify the long-term decline in lung function that is the hallmark of this disease (Evidence A).
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